What is stress? Do you really know? Featured by Arizona Center for Advanced Medicine treating 300+ holistic and medical conditions in Phoenix at the expanded Scottsdale center. Call 480-240-2600.
What is Stress?
Submitted by Dr. Martha Grout, M.D., M.D.(H) Arizona Center for Advanced Medicine, Scottsdale (Phoenix), Az.
Dr Martha Grout explains “A patient gave me an article on stress from the Massachusetts General Hospital Departments of Psychiatry and Cardiology – that’s an appropriate combination.”
The title of the article is “Depression and Failure of Cholesterol Lowering after Acute Myocardial Infarction”.[1] The authors were linking depression with higher cholesterol levels and higher mortality after a heart attack, despite treatment with statin drugs like Lipitor®, and suggesting that lowering the cholesterol further might help treat the depression.
In the discussion section of the article, they did mention that depression in a of itself may cause elevated cholesterol levels because of the effect of stress hormones raising cortisol levels. High cortisol levels are associated with high cholesterol levels.
So it would make sense to work on the high cortisol levels, right? Treat the stress (or the depression), treat the cortisol, lower the cholesterol and
decrease mortality from heart attacks.
So why does the body raise its cholesterol levels in the first place? Cholesterol is at the head of the chain that manufactures things like Vitamin D, sex hormones and cortisol.
Cortisol? Isn’t that what is produced in response to stress? Hm’m’m…
Most of us associate the word “stress” with the word “emotional” – i.e. emotion-based, with all the associated factors relating to difficulty coping with a given situation.
![]()
View a new video “Stress” by Arizona Center for Advanced Medicine, click here >>
.
We know that stress impacts the body, because we see it all the time. Monday morning heart attacks. Death of a spouse followed within a short time by death of the partner. Heartburn. Agida. Asthma. Depression. Anxiety. The list goes on…[1]
We use these concepts in our metaphors. How often do we hear things like “died of a broken heart”, or talk about how some situation may give us “heartburn”. Clearly we are comfortable with the idea that the heart is somehow associated with emotion.
We even have evidence of physiologic change in the organism under stress.
View other articles on Stress, click here >>
http://goo.gl/CC88D
.
View other articles on Cholesterol, click here >>
http://goo.gl/fFo9E
.
With acute stress, we see the “fight, flight, freeze” response – racing heart, emptying of the bowels and bladder, hyperfocus on the stress-inducer to the exclusion of everything else. The result may be belligerence, or running away, or simply paralysis – depending upon whether there is a perceived way out.
Our bodies are very finely tuned machines, and have developed over the course of our evolution many ways of dealing with problems that we have all the time, every day. Cortisol is one of those mechanisms. But cortisol doesn’t just come out of thin air. It has to be manufactured by the adrenal glands, in response to a signal from the pituitary gland in the brain that recognizes the need for more cortisol. And if cortisol causes us to lay down more cholesterol, there may be a good physiologic reason.
Maybe we with our pharmaceutical drugs are trying to put the cart before the horse.
View FREE video “Chemicals that harm us”, click here >>
http://goo.gl/2BVYi
Does the answer to stress actually lie in the realm of perception rather than entirely in the realm of the physical?
Might we actually have really good control of stress if we can simply change our attitude about it?
That sounds simplistic, doesn’t it? But there is plenty of evidence that control of our reaction is key to changing our response to stress.[1]
We tend to feel more stress when we see no way out of our situation. Rats raised in isolation are under severe stress, and die at a younger age
than rats raised in a group. So do people.[2] When the isolated rats are given nesting material, they heal from wounds faster.[3] Stress early in life, as well as isolation later in life, is associated with reduced longevity, both in birds[4] and in people.[5]
So what can we do about stress? The serenity prayer written by the German theologian Reinhold Niebuhr is one really good solution:
“God, grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference.”
That pretty much sums it up. Each of us has control over only one person’s behavior – our own. We have the choice, to keep running in the squirrel cage, or to look up and find the door in the ceiling, the way out of the box.
The Arizona Center for Advanced Medicine reminds us “We have the choice.”

<p><a href=”http://vimeo.com/47271052″>Stress</a> from <a href=”http://vimeo.com/malcolmpro”>Malcolm Matusky</a> on <a href=”http://vimeo.com”>Vimeo</a>.</p>
Bookmark this page to check back in a few days to view a brand new video “Stress” by Arizona Center for Advanced Medicine.

[1] Huffman JC, Smith FA et al. Depression and failure of cholesterol lowering after acute myocardial infarction. Prim Care Companion J Clin Psychiatry. 2010;12(1):PCC.08m00766.
[2] Ivy AS, Brunson KL et al. Dysfunctional nurturing behavior in rat dams with limited access to nesting material: a clinically relevant model for early-life stress. Neuroscience. 2008 Jun 26;154(3):1132-42.
[3] Endrighi R, Hamer M et al. Associations of trait optimism with diurnal neuroendocrine activity, cortisol responses to mental stress, and subjective stress measures in healthy men and women. Psychosom Med. 2011 Oct;73(8):672-8.
[4] Brody JE. Communities Learn the Good Life Can Be a Killer. New York Times January 30, 2012
[5] Vitalo AG, Gorantla S et al. Environmental enrichment with nesting material accelerates wound healing in isolation-reared rats. Behav Brain Res. 2012 Jan 15;226(2):606-12.
[6] Monaghan P, Heindinger B et al. For better or worse: reduced adult lifespan following early-life stress is transmitted to breeding partners. Proc. R. Soc. B 22 February 2012 vol. 279 no. 1729 709-714.
[7] Friedman E, Thomas SA et al. Relationship of depression, anxiety, and social isolation to chronic heart failure outpatient mortality. American Heart Journal 152;5:940e1 – 940e8, November 2006.

Arizona Center for Advanced Medicine has provided links to additional information below:
Communities Learn the Good Life can be a Killer.
By Christopher T. Martin
ACTIVE ANTIDOTE Atlanta is transforming an old rail corridor into a trail network that encourages walking and biking.
Developers in the last half-century called it progress when they built homes and shopping malls far from city centers throughout the country, sounding the death knell for many downtowns. But now an alarmed cadre of public health experts say these expanded metropolitan areas have had a far more serious impact on the people who live there by creating vehicle-dependent environments that foster obesity, poor health, social isolation, excessive stress and depression.
As a result, these experts say, our “built environment” — where we live, work, play and shop — has become a leading cause of disability and death in the 21st century. Physical activity has been disappearing from the lives of young and old, and many communities are virtual “food deserts,” serviced only by convenience stores that stock nutrient-poor prepared foods and drinks.
View the complete NY Times article, click here >>
http://goo.gl/sprmF
.

Early Life Stress Harms Mental Function and Immune System in Later Years, According to New Research.
ScienceDaily (Oct. 30, 2004) — Evidence continues to mount that prenatal and early experience can have profound long-term effects on the developing central nervous system and its regulation of basic physiology, psychology, and immune function. Several reports at the Society For Neuroscience annual meeting demonstrate that this phenomenon is conserved across species-from the barn owl to rodents to humans-suggesting that these effects are mediated by fundamental mechanisms.
Insight into one potential mechanism comes from studies showing how maternal care can induce alterations in gene methylation in offspring. Other new research is uncovering how stresses during pregnancy and early life can affect learning and memory, as well as immune function, much later in life, long after the stress has disappeared. Still other studies are unraveling the cellular basis for how early life stresses can lead to later cognitive impairment, the effects of using selective serotonin reuptake inhibitors such as Prozac during early development on the emotional behavior of adult mice, and how experience—hunting in the case of barn owls—can dramatically increase adult animals’ adaptability to new stimuli. Together, these studies point to exciting new approaches for potentially lessening or preventing these long-term changes that can lead to disease or psychopathologies.
![]()
View the complete Science Daily article, click here >>
http://goo.gl/6DzUp
.

Give the Arizona Center for Advanced Medicine Scottsdale Center a call to schedule a time to come see us, visit our new beautiful expanded clinic, ask lots of questions, and make an informed decision for good health.
The Arizona Center for Advanced Medicine treats over 300+ conditions. Contact Arizona Center for Advanced Medicine for a FREE consultation at 480-240-2600, or click here >>
http://goo.gl/R2cGE
.
Review real patient testimonials and videos, click here >>
http://goo.gl/hANEh
.
View the entire Arizona Center for Advanced Medicine Cancer Series articles, click here >>
http://goo.gl/VFLmD
.
Thank you for viewing the Arizona Center for Advanced Medicine blog. We want your OPINION, please take just one minute to VOTE, click here >>
http://goo.gl/JnzMT
.
Order Dr Martha Grout’s new book “An Alphabet of Good Health in a Sick World” and view more information on this featured book and how to ORDER with a special offer, click here >>
http://goo.gl/lgwqi
.
Hear Dr. Grout’s radio show interview on “Good Health in a Sick World”, (the actual interview starts at 4:14 minutes) click here >>
http://goo.gl/gnihJ
.
Find, Follow, LIKE and See us everywhere at ‘AdvancedMedAZ’.
If you lower your cholesterol, will your risk of cancer increase? #10 Featured by Arizona Center for Advanced Medicine treating 300+ holistic and medical conditions in Phoenix, AZ, at our newly expanded Scottsdale, Arizona center. Call 480-240-2600.
Cancer Series #10- Lower your cholesterol; increase your risk of cancer?
Submitted by as part of the 2012 Cancer Series of articles by Dr. Martha Grout, M.D., M.D.(H) at the Arizona Center for Advanced Medicine Cancer Center, Scottsdale (Phoenix), Az.
But aren’t statins supposed to be the good guys? The New England Journal of Medicine published an article in May 2012 that states:
“Over a period of 4 years of statin use, a reduction of 1 mmol per liter (39 mg per deciliter) in the level of low-density lipoprotein (LDL) cholesterol translates into a 9% reduction in the risk of death from any cause among patients with diabetes and a 13% reduction among those without diabetes.”[1]
That’s hard to beat. Take a pill, reduce your risk of heart attack and death by up to 13%. The article goes on to say: “Few drugs have had such a dramatic effect on health outcomes.”
The Journal of Clinical Lipidology published an article in the same month stating: “A better understanding of the characteristics of current and former statin users may be helpful for formulating strategies to improve long-term adherence.”[2] The conclusion of the article was that most patients who stopped taking their statins did so because of the side effects. The conclusion of this article was, interestingly enough, that we can increase compliance with taking the statin if only we talk more with our patients and explain to them how important it is.
If I were to take a medication and it made me feel really bad, I would want to know why it made me feel bad. What I find missing in the scientific literature about side effects from statins is any sense of concern that the side effects might represent something really important, and maybe we should figure it out before we continue to push the drugs.
View the article “High Cholesterol – 29 billion reasons to treat it”, click here >>
http://goo.gl/jMkZA
.
But wait… taking statins also appears to increase the risk of developing diabetes, in a dose-dependent manner – the higher the dose of a statin
drug, the greater the risk of diabetes. [3] Diabetics are more likely to develop cancer than non-diabetics.[4]
The New York Times published a piece[5] in early March 2012 entitled: The Diabetes Dilemma for Statin Users. They note that about 1 in every 200 people who take statin drugs will develop diabetes simply because of taking the drug for as little as five years. That covers a pretty good segment of the adult population, 100,000 new diabetics. If you are one of the people without heart disease who are taking statins prophylactically, or “just because it will prevent a heart attack”, I recommend that you think again, and perhaps make a different choice.
![]()
View the entire New York Times article, click here >>
http://goo.gl/nNCQk
.
The Federal Drug Administration (FDA) even put out a warning about statin drugs: “Increases in glycosylated hemoglobin (HbA1c) and fasting serum glucose levels have been reported with statin use.”[6]
And besides, one really wonders how much of the benefit of statin drugs to those who have already had a heart attack comes from changing of lifestyle. The authors of a paper about adherence to a regimen of statin drugs in older adults suggested that “patients initiating and adhering to chronic preventive drug therapies are more likely to engage in other health-promoting behaviors. Failure to account for this relationship may introduce bias in any epidemiologic study evaluating the effect of a preventive therapy on clinical outcomes.” [7]
In other words, it is not at all clear whether lowering cholesterol by means of statin drugs is as healthy as the manufacturers of said statin drugs would like us to believe.
Remind me again why I would want to take a drug whose “side effects” include muscle aches, chronic fatigue, heart failure, diabetes, cancer and memory loss?
Just because “the doctor said so” is not sufficient reason to engage in risky behavior.
We do have a choice. We can vote both with our pocketbooks and with our choice of lifestyle. We do not have to fill the prescription.
We can choose to eat fruits and vegetables. We can even choose to eat them organically grown. We can choose to limit our portions of animal based proteins. We can choose to avoid osteoporosis-inducing sodas and cancer-inducing artificial sweeteners.
We can choose to avoid unnecessary drugs.
The Arizona Center for Advanced Medicine reminds us, “We have a choice”.
View the “When will people “get it” video with Dr Martha Grout, below…
View the other Cancer Series articles, click here >>
http://goo.gl/8AU1g
.
![]()
http://goo.gl/uQk1k
.
Arizona Center for Advanced Medicine patient Pat Reale ”My Cancer” by Malcolm Matusky on Vimeo.
[1] Goldfine AB. Statins: Is It Really Time to Reassess Benefits and Risks? N Engl J Med 2012; 366:1752-1755 May 10, 2012.
[2] Cohen JD, Brinton EA et al. Journal of Clinical Lipidology. 6;3: 208-215 (May 2012)
[3] Culver AL, Ockene ISs et al. Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the Women’s Health Initiative. Arch Intern Med. 2012;172(2):144-152. doi:10.1001/archinternmed.2011.625.
[4] Bodmer M, Becker C et al. Use of Antidiabetic Agents and the Risk of Pancreatic Cancer: A Case–Control Analysis. Am J Gastroenterol. 2012 Apr;107(4):620-6. doi: 10.1038/ajg.2011.483.
[5] The Diabetes Dilemma for Statin Users downloaded 6/24/2012
[6] FDA Drug Safety Communication: Important safety label changes to cholesterol-lowering statin drugs. Downloaded 6/24/2012
[7] Patrick AR, Shrank WH et al. The association between statin use and outcomes potentially attributable to an unhealthy lifestyle in older adults. Value Health. 2011 Jun;14(4):513-20.
![]()
Give the Arizona Center for Advanced Medicine Scottsdale Center a call to schedule a time to come see us, visit our new beautiful expanded clinic, ask lots of questions, and make an informed decision for good health. View a video introduction, click here >>
http://goo.gl/jRYOV
.
The Arizona Center for Advanced Medicine treats over 300+ conditions. Contact Arizona Center for Advanced Medicine for a FREE consultation at 480-240-2600, or click here >>
http://goo.gl/R2cGE
.

Make an APPOINTMENT ONLINE, Fast and Easy, click here >>
http://goo.gl/p2lnZ
.
Thank you for viewing the Arizona Center for Advanced Medicine blog. We want your OPINION, please take just one minute to VOTE, click here >>
http://goo.gl/JnzMT
.
Order Dr Martha Grout’s new book “An Alphabet of Good Health in a Sick World” and view more information on this featured book and how to ORDER with a special offer, click here >>
http://goo.gl/lgwqi
.
Hear Dr. Grout’s radio show interview on “Good Health in a Sick World”, (the actual interview starts at 4:14 minutes) click here >>
http://goo.gl/gnihJ
.
Find, Follow, LIKE and See us everywhere at ‘AdvancedMedAZ’.
If you lower your cholesterol, will your risk of cancer increase? #10 Featured by Arizona Center for Advanced Medicine treating 300+ holistic and medical conditions in Phoenix, AZ, at our newly expanded Scottsdale, Arizona center. Call 480-240-2600.
Cancer Series #10- Lower your cholesterol; increase your risk of cancer?
Submitted by as part of the 2012 Cancer Series of articles by Dr. Martha Grout, M.D., M.D.(H) at the Arizona Center for Advanced Medicine Cancer Center, Scottsdale (Phoenix), Az.
But aren’t statins supposed to be the good guys? The New England Journal of Medicine published an article in May 2012 that states:
“Over a period of 4 years of statin use, a reduction of 1 mmol per liter (39 mg per deciliter) in the level of low-density lipoprotein (LDL) cholesterol translates into a 9% reduction in the risk of death from any cause among patients with diabetes and a 13% reduction among those without diabetes.”[1]
That’s hard to beat. Take a pill, reduce your risk of heart attack and death by up to 13%. The article goes on to say: “Few drugs have had such a dramatic effect on health outcomes.”
The Journal of Clinical Lipidology published an article in the same month stating: “A better understanding of the characteristics of current and former statin users may be helpful for formulating strategies to improve long-term adherence.”[2] The conclusion of the article was that most patients who stopped taking their statins did so because of the side effects. The conclusion of this article was, interestingly enough, that we can increase compliance with taking the statin if only we talk more with our patients and explain to them how important it is.
If I were to take a medication and it made me feel really bad, I would want to know why it made me feel bad. What I find missing in the scientific literature about side effects from statins is any sense of concern that the side effects might represent something really important, and maybe we should figure it out before we continue to push the drugs.
View the article “High Cholesterol – 29 billion reasons to treat it”, click here >>
http://goo.gl/jMkZA
.
But wait… taking statins also appears to increase the risk of developing diabetes, in a dose-dependent manner – the higher the dose of a statin
drug, the greater the risk of diabetes. [3] Diabetics are more likely to develop cancer than non-diabetics.[4]
The New York Times published a piece[5] in early March 2012 entitled: The Diabetes Dilemma for Statin Users. They note that about 1 in every 200 people who take statin drugs will develop diabetes simply because of taking the drug for as little as five years. That covers a pretty good segment of the adult population, 100,000 new diabetics. If you are one of the people without heart disease who are taking statins prophylactically, or “just because it will prevent a heart attack”, I recommend that you think again, and perhaps make a different choice.
![]()
View the entire New York Times article, click here >>
http://goo.gl/nNCQk
.
The Federal Drug Administration (FDA) even put out a warning about statin drugs: “Increases in glycosylated hemoglobin (HbA1c) and fasting serum glucose levels have been reported with statin use.”[6]
And besides, one really wonders how much of the benefit of statin drugs to those who have already had a heart attack comes from changing of lifestyle. The authors of a paper about adherence to a regimen of statin drugs in older adults suggested that “patients initiating and adhering to chronic preventive drug therapies are more likely to engage in other health-promoting behaviors. Failure to account for this relationship may introduce bias in any epidemiologic study evaluating the effect of a preventive therapy on clinical outcomes.” [7]
In other words, it is not at all clear whether lowering cholesterol by means of statin drugs is as healthy as the manufacturers of said statin drugs would like us to believe.
Remind me again why I would want to take a drug whose “side effects” include muscle aches, chronic fatigue, heart failure, diabetes, cancer and memory loss?
Just because “the doctor said so” is not sufficient reason to engage in risky behavior.
We do have a choice. We can vote both with our pocketbooks and with our choice of lifestyle. We do not have to fill the prescription.
We can choose to eat fruits and vegetables. We can even choose to eat them organically grown. We can choose to limit our portions of animal based proteins. We can choose to avoid osteoporosis-inducing sodas and cancer-inducing artificial sweeteners.
We can choose to avoid unnecessary drugs.
The Arizona Center for Advanced Medicine reminds us, “We have a choice”.
View the other Cancer Series articles, click here >>
http://goo.gl/8AU1g
.
![]()
http://goo.gl/uQk1k
.
Arizona Center for Advanced Medicine patient Pat Reale “My Cancer” by Malcolm Matusky on Vimeo.
[1] Goldfine AB. Statins: Is It Really Time to Reassess Benefits and Risks? N Engl J Med 2012; 366:1752-1755 May 10, 2012.
[2] Cohen JD, Brinton EA et al. Journal of Clinical Lipidology. 6;3: 208-215 (May 2012)
[3] Culver AL, Ockene ISs et al. Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the Women’s Health Initiative. Arch Intern Med. 2012;172(2):144-152. doi:10.1001/archinternmed.2011.625.
[4] Bodmer M, Becker C et al. Use of Antidiabetic Agents and the Risk of Pancreatic Cancer: A Case–Control Analysis. Am J Gastroenterol. 2012 Apr;107(4):620-6. doi: 10.1038/ajg.2011.483.
[5] The Diabetes Dilemma for Statin Users downloaded 6/24/2012
[6] FDA Drug Safety Communication: Important safety label changes to cholesterol-lowering statin drugs. Downloaded 6/24/2012
[7] Patrick AR, Shrank WH et al. The association between statin use and outcomes potentially attributable to an unhealthy lifestyle in older adults. Value Health. 2011 Jun;14(4):513-20.
![]()
Give the Arizona Center for Advanced Medicine Scottsdale Center a call to schedule a time to come see us, visit our new beautiful expanded clinic, ask lots of questions, and make an informed decision for good health. View a video introduction, click here >>
http://goo.gl/jRYOV
.
The Arizona Center for Advanced Medicine treats over 300+ conditions. Contact Arizona Center for Advanced Medicine for a FREE consultation at 480-240-2600, or click here >>
http://goo.gl/R2cGE
.

Make an APPOINTMENT ONLINE, Fast and Easy, click here >>
http://goo.gl/p2lnZ
.
Thank you for viewing the Arizona Center for Advanced Medicine blog. We want your OPINION, please take just one minute to VOTE, click here >>
http://goo.gl/JnzMT
.
Order Dr Martha Grout’s new book “An Alphabet of Good Health in a Sick World” and view more information on this featured book and how to ORDER with a special offer, click here >>
http://goo.gl/lgwqi
.
Hear Dr. Grout’s radio show interview on “Good Health in a Sick World”, (the actual interview starts at 4:14 minutes) click here >>
http://goo.gl/gnihJ
.
Find, Follow, LIKE and See us everywhere at ‘AdvancedMedAZ’.
What is stress? Do you really know? Featured by Arizona Center for Advanced Medicine treating 300+ holistic and medical conditions in Phoenix at the expanded Scottsdale center. Call 480-240-2600.
What is Stress?
Submitted by Dr. Martha Grout, M.D., M.D.(H) and Dr. Jonathan Murphy, M.D.
Arizona Center for Advanced Medicine, Scottsdale (Phoenix), Az.
Dr Martha Grout explains “A patient gave me an article on stress from the Massachusetts General Hospital Departments of Psychiatry and Cardiology – that’s an appropriate combination.”
The title of the article is “Depression and Failure of Cholesterol Lowering after Acute Myocardial Infarction”.[1] The authors were linking depression with higher cholesterol levels and higher mortality after a heart attack, despite treatment with statin drugs like Lipitor®, and suggesting that lowering the cholesterol further might help treat the depression.
In the discussion section of the article, they did mention that depression in an of itself may cause elevated cholesterol levels because of the effect of stress hormones raising cortisol levels. High cortisol levels are associated with high cholesterol levels.
So it would make sense to work on the high cortisol levels, right? Treat the stress (or the depression), treat the cortisol, lower the cholesterol and
decrease mortality from heart attacks.
So why does the body raise its cholesterol levels in the first place? Cholesterol is at the head of the chain that manufactures things like Vitamin D, sex hormones and cortisol.
Cortisol? Isn’t that what is produced in response to stress? Hm’m’m…
Most of us associate the word “stress” with the word “emotional” – i.e. emotion-based, with all the associated factors relating to difficulty coping with a given situation.
![]()
View a new video “Stress” by Arizona Center for Advanced Medicine, click here >>
.
We know that stress impacts the body, because we see it all the time. Monday morning heart attacks. Death of a spouse followed within a short time by death of the partner. Heartburn. Agida. Asthma. Depression. Anxiety. The list goes on…[1]
We use these concepts in our metaphors. How often do we hear things like “died of a broken heart”, or talk about how some situation may give us “heartburn”. Clearly we are comfortable with the idea that the heart is somehow associated with emotion.
We even have evidence of physiologic change in the organism under stress.
View other articles on Stress, click here >>
http://goo.gl/CC88D
.
View other articles on Cholesterol, click here >>
http://goo.gl/fFo9E
.
With acute stress, we see the “fight, flight, freeze” response – racing heart, emptying of the bowels and bladder, hyperfocus on the stress-inducer to the exclusion of everything else. The result may be belligerence, or running away, or simply paralysis – depending upon whether there is a perceived way out.
Our bodies are very finely tuned machines, and have developed over the course of our evolution many ways of dealing with problems that we have all the time, every day. Cortisol is one of those mechanisms. But cortisol doesn’t just come out of thin air. It has to be manufactured by the adrenal glands, in response to a signal from the pituitary gland in the brain that recognizes the need for more cortisol. And if cortisol causes us to lay down more cholesterol, there may be a good physiologic reason.
Maybe we with our pharmaceutical drugs are trying to put the cart before the horse.
View FREE video “Chemicals that harm us”, click here >>
http://goo.gl/2BVYi
Does the answer to stress actually lie in the realm of perception rather than entirely in the realm of the physical?
Might we actually have really good control of stress if we can simply change our attitude about it?
That sounds simplistic, doesn’t it? But there is plenty of evidence that control of our reaction is key to changing our response to stress.[1]
We tend to feel more stress when we see no way out of our situation. Rats raised in isolation are under severe stress, and die at a younger age
than rats raised in a group. So do people.[2] When the isolated rats are given nesting material, they heal from wounds faster.[3] Stress early in life, as well as isolation later in life, is associated with reduced longevity, both in birds[4] and in people.[5]
So what can we do about stress? The serenity prayer written by the German theologian Reinhold Niebuhr is one really good solution:
“God, grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference.”
That pretty much sums it up. Each of us has control over only one person’s behavior – our own. We have the choice, to keep running in the squirrel cage, or to look up and find the door in the ceiling, the way out of the box.
The Arizona Center for Advanced Medicine reminds us “We have the choice.”

<p><a href=”http://vimeo.com/47271052″>Stress</a> from <a href=”http://vimeo.com/malcolmpro”>Malcolm Matusky</a> on <a href=”http://vimeo.com”>Vimeo</a>.</p>
Bookmark this page to check back in a few days to view a brand new video “Stress” by Arizona Center for Advanced Medicine.

[1] Huffman JC, Smith FA et al. Depression and failure of cholesterol lowering after acute myocardial infarction. Prim Care Companion J Clin Psychiatry. 2010;12(1):PCC.08m00766.
[2] Ivy AS, Brunson KL et al. Dysfunctional nurturing behavior in rat dams with limited access to nesting material: a clinically relevant model for early-life stress. Neuroscience. 2008 Jun 26;154(3):1132-42.
[3] Endrighi R, Hamer M et al. Associations of trait optimism with diurnal neuroendocrine activity, cortisol responses to mental stress, and subjective stress measures in healthy men and women. Psychosom Med. 2011 Oct;73(8):672-8.
[4] Brody JE. Communities Learn the Good Life Can Be a Killer. New York Times January 30, 2012
[5] Vitalo AG, Gorantla S et al. Environmental enrichment with nesting material accelerates wound healing in isolation-reared rats. Behav Brain Res. 2012 Jan 15;226(2):606-12.
[6] Monaghan P, Heindinger B et al. For better or worse: reduced adult lifespan following early-life stress is transmitted to breeding partners. Proc. R. Soc. B 22 February 2012 vol. 279 no. 1729 709-714.
[7] Friedman E, Thomas SA et al. Relationship of depression, anxiety, and social isolation to chronic heart failure outpatient mortality. American Heart Journal 152;5:940e1 – 940e8, November 2006.

Arizona Center for Advanced Medicine has provided links to addtional information below:
Communities Learn the Good Life can be a Killer.
By Christopher T. Martin
ACTIVE ANTIDOTE Atlanta is transforming an old rail corridor into a trail network that encourages walking and biking.
Developers in the last half-century called it progress when they built homes and shopping malls far from city centers throughout the country, sounding the death knell for many downtowns. But now an alarmed cadre of public health experts say these expanded metropolitan areas have had a far more serious impact on the people who live there by creating vehicle-dependent environments that foster obesity, poor health, social isolation, excessive stress and depression.
As a result, these experts say, our “built environment” — where we live, work, play and shop — has become a leading cause of disability and death in the 21st century. Physical activity has been disappearing from the lives of young and old, and many communities are virtual “food deserts,” serviced only by convenience stores that stock nutrient-poor prepared foods and drinks.
View the complete NY Times article, click here >>
http://goo.gl/sprmF
.

Early Life Stress Harms Mental Function and Immune System in Later Years, According to New Research.
ScienceDaily (Oct. 30, 2004) — Evidence continues to mount that prenatal and early experience can have profound long-term effects on the developing central nervous system and its regulation of basic physiology, psychology, and immune function. Several reports at the Society For Neuroscience annual meeting demonstrate that this phenomenon is conserved across species-from the barn owl to rodents to humans-suggesting that these effects are mediated by fundamental mechanisms.
Insight into one potential mechanism comes from studies showing how maternal care can induce alterations in gene methylation in offspring. Other new research is uncovering how stresses during pregnancy and early life can affect learning and memory, as well as immune function, much later in life, long after the stress has disappeared. Still other studies are unraveling the cellular basis for how early life stresses can lead to later cognitive impairment, the effects of using selective serotonin reuptake inhibitors such as Prozac during early development on the emotional behavior of adult mice, and how experience—hunting in the case of barn owls—can dramatically increase adult animals’ adaptability to new stimuli. Together, these studies point to exciting new approaches for potentially lessening or preventing these long-term changes that can lead to disease or psychopathologies.
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View the complete Science Daily article, click here >>
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High Cholesterol – 29 billion reasons to treat it. Featured by Arizona Center for Advanced Medicine treating 300+ holistic and medical conditions our new expanded Scottsdale, AZ, clinic. Call 480-240-2600.
High Cholesterol – 29 billion reasons to treat it.
Submitted by Dr. Martha Grout, M.D., M.D.(H) and Dr. Jonathan Murphy, M.D.
Arizona Center for Advanced Medicine, Scottsdale (Phoenix), Az.
29 billion what? Patients? Dollars? Prescriptions?
Did you ever wonder what was the big hype about cholesterol?
Or did you simply accept that high cholesterol is bad, and not even think about it? Kind of like “cover yourself with sunscreen so you don’t get skin cancer” or “the sun rises in the East and sets in the West” – something that is so much a part of our mindset and everyday life that we don’t even notice it, much less question it.
A documentary film carries the title: “High Cholesterol – 29 billion reasons to treat it.”
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View the film preview “29 Billion Reasons to Lie About Cholesterol”, click here >>
http://goo.gl/O1Mwc
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Before the 1950s, cholesterol was not even part of medical thinking, except on the part of researchers.
The idea that cholesterol causes coronary heart disease started in the early 1900′s when extremely high amounts of dietary (powdered and oxidized) cholesterol were fed to rabbits. Their blood cholesterol rose twenty-fold and a soft plaque like substance formed on the coronary arteries. Cholesterol levels returned to normal and the plaque disappeared when the feeding was stopped.
In the late 1950′s, Ancel Keys proposed that the more saturated fat you ate, the higher your cholesterol; the higher the cholesterol (in rabbits), the more plaque and presumed cardio-vascular disease. This gave birth to the “lipid theory” that dietary cholesterol is downright dangerous because it directly causes atherosclerosis.
The Federal Drug Administration (FDA) website has an interesting history of the development of cholesterol-lowering drugs – the statins.[1] By 1979 Merck scientists had isolated lovastatin, a compound which inhibits the synthesis of cholesterol.
However, a clinical study using clofibrate which binds cholesterol in the intestine resulted in significantly higher mortality in the drug-treated
group. Not surprisingly, the pharmaceutical interest in cholesterol-lowering therapy evaporated.
In 1984, the Lipid Research Clinics Coronary Primary Prevention Trial, funded in part by Proctor and Gamble (manufacturer of margarine andsaturated vegetable oils) placed all subjects on a low cholesterol, low saturated fat diet (through the use of margarine, egg replacers, processed cheese and baked goods made with vegetable shortenings). One group took a cholesterol lowering drug, one group a placebo. Results of the study purportedly showed that the group taking the cholesterol lowering drugs had a lower incidence of death from heart disease.
Rarely mentioned was the conclusion that the group which took cholesterol lowering drugs also had an increase in deaths from cancer, stroke, violence and suicide.
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View FREE video “Understanding Cholesterol”, click here >>
http://goo.gl/mqIO7
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And when the data was re-analyzed by the lipid group from theUniversity ofMaryland, no difference was found between the two groups in the incidence of coronary heart disease.
In 1984 the Journal of the American Medical Association (JAMA) published results from the Lipid Research Clinic Coronary Primary Prevention Trial (LRCCPPT) which used cholestyramine and dietary changes. The study showed a decrease in deaths from coronary artery disease.
Suddenly there was renewed interest in the media.
In 1984, the National Heart, Lung and Blood Institute (NHLBI) convened the Cholesterol Consensus Conference, ostensibly to bring together the proponents of the cholesterol theory with the dissidents. It appears that the report was written prior to the actual convening of the conference[1], simply leaving a few spaces to plug in the numbers to be considered as “elevated” cholesterol.
Is it a coincidence that Merck’s re-application for new drug status was sent to the FDA in 1984?
In November 1986 the Journal of the American Medical Association (JAMA) published a series on the lipid clinical trials[2].
In 1988, at a lecture given before the American Heart Association, DeWitt S Goodman MD spoke about the many efforts which were being made to educate both patients and physicians in the benefits of treating high cholesterol levels (defined at that time as being over 240).
A physician’s packet was prepared by the Physicians Cholesterol Education Program in 1987. Mary Enig writes that the American Pharmaceutical Association had representatives on the coordinating committee.[3]
Is it also a coincidence that Merck’s lovastatin (Lipitor®) was approved by the FDA in 1987, one of the shortest times on record for approval of a new drug?
Probably the most painstaking analyses of the Keyes data was published in 2001 in a book entitled The Cholesterol Myths: Exposing the Fallacy that Saturated Fat and Cholesterol Cause Heart Disease by Dr. Uffe Ravnskov.[4]
“People with high cholesterol live the longest. This statement seems so incredible that it takes a long time to clear one’s brainwashed mind to fully understand its importance. Yet the fact that people with high cholesterol live the longest emerges clearly from many scientific papers.”
And the battle rages on… and on… and on.
The Lancet just published an article with the title “Statins for all by the age of 50 years?”, click here to view complete article >>
http://goo.gl/wJd30
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How do we deal with the issue at the Arizona Center for Advanced Medicine?
We work with diet – healthy real food, meats, fish, fruits and vegetables – healthy fats – fish oils, coconut oils, olive oil, butter – healthy drinks – no artificial sweeteners (except Stevia, which so far does not seem to have a down-side).
We work with nutrition – adequate vitamins and minerals, through diet or supplementation, to give the engine sufficient gas to allow it to run.
We work with exercise – enough fresh air and moving around to get the blood flowing, giving the engine sufficient lubrication to allow the parts to move freely.
We work with detoxification – getting rid of chemicals, allergens, heavy metals and toxic emotions, to allow the body to function normally, without being weight down by things which it no longer needs, cleaning up the carburetors.
We work with attitude – we tend to get back what we project, so let’s make sure we are projecting love and healing. That would be the basis of the golden rule. If our tailpipe puts out smoke and bad smells, these will almost certainly come back at us through our open windows.
Structure is crucial to our function, and cholesterol is crucial to our structure.
As with so many other things, balance is essential to our existence.
We do not believe that anyone ever died of a deficiency of lovastatin. We do believe that diet and exercise are the best treatment to prevent heart disease and promote a healthy life.
The Arizona Center for Advanced Medicine reminds you, “The choice is yours.”
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[2]
http://www.westonaprice.org/know-your-fats/the-oiling-of-america#national
[3] S M Grundy, “Cholesterol and Coronary Heart Disease: A New Era,” JAMA, Nov 28, 1986, 256:(20):2849-2858
[4]
http://www.westonaprice.org/know-your-fats/the-oiling-of-america#national
[5] Now out of print, available on Amazon used.
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Listed below, the Arizona Center for Advanced Medicine has researched some additional related information that you may be interested in:
“29 billion reasons to lie about cholesterol.”
Film Synopsis:
We are told that cholesterol is a major cause of heart disease. At least 40 million people are currently taking cholesterol-lowering medications, known as statins, and millions more people are avoiding foods that contain saturated fat and cholesterol.
However, a numbers of doctors and researchers have been challenging this hypothesis for decades, and the latest heart disease statistics reveal some alarming facts.
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View the film’s website and preview, click here >>
http://goo.gl/1X5NO
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In The Lancet, the Cholesterol Treatment Trialists’ (CTT) Collaborators report a relative risk reduction on statins of about 20% (RR 0.79, 95% CI 0.77—0.81) for major vascular events per 1 mmol/L reduction in LDL cholesterol across different levels of cardiovascular risk.1 Men and women, old and young, and people with and without cardiovascular disease all benefit. These findings confirm the efficacy of statins for primary prevention, resolving concerns about possible serious adverse effects and potential sources of bias in randomised trials.2 The report extends findings to lower levels of cardiovascular disease risk than is recommended by existing guidelines in theUSA, Europe, and theUK, and shows that benefits of statins outweigh any conceivable serious adverse effects. The study raises questions for clinical practice. Are the opportunity costs in primary care acceptable? Can LDL cholesterol reductions of 1 mmol/L be sustained in routine primary care? Are statins cost effective for patients at low cardiovascular disease risk?
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View the complete article, click here >>
http://goo.gl/wJd30
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Background
Statins reduce LDL cholesterol and prevent vascular events, but their net effects in people at low risk of vascular events remain uncertain.
Findings
Reduction of LDL cholesterol with a statin reduced the risk of major vascular events (RR 0.79, 95% CI 0.77—0.81, per 1.0 mmol/L reduction), largely irrespective of age, sex, baseline LDL cholesterol or previous vascular disease, and of vascular and all-cause mortality.
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View the complete article, click here >>
http://goo.gl/wJd30
.
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Cholesterol and Coronary Heart diease: A New Era
SEVERAL important developments have recently given new impetus to prevention of coronary heart disease (CHD) through control of the plasma cholesterol level. Three advances have been particularly dramatic. First, the Nobel prize in medicine was awarded in 1985 to Drs Joseph Goldstein and Michael Brown for their discovery of cell-surface receptors for low-density lipoproteins (LDLs); their finding was fundamental to our understanding of how plasma cholesterol levels are controlled. Second, the Lipid Research Clinics (LRC) Coronary Primary Prevention Trial (CPPT)1 reported that lowering of the plasma cholesterol level by bile acid sequestrants reduces the frequency of several manifestations of CHD, including myocardial infarction. And third, a new class of cholesterollowering drugs, namely, competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme in cholesterol synthesis, has been shown to markedly lower cholesterol levels.2-4 Although these inhibitors are not yet approved for clinical use, they reveal the potential for …
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View the entire article, click here >>
http://goo.gl/TfubC
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Give the Arizona Center for Advanced Medicine Scottsdale Center a call to schedule a time to come see us, visit our new beautiful expanded clinic, ask lots of questions, and make an informed decision for good health.
The Arizona Center for Advanced Medicine treats over 300+ conditions. Contact Arizona Center for Advanced Medicine for a FREE consultation at 480-240-2600, or click here >>
http://goo.gl/R2cGE
Order Dr Martha Grout’s new book “An Alphabet of Good Health in a Sick World”
More information on Dr Grout’s book and to ORDER with a special offer, click here >>
http://goo.gl/aDihW
.
Hear Dr. Grout’s radio show interview on “Good Health in a Sick World”, (the actual interview starts at 4:14 minutes) click here >>
http://goo.gl/gnihJ
Find, Follow, LIKE and See us everywhere at ‘AdvancedMedAZ’.
Do our bodies REALLY intend to hurt us? High cholesterol might. Featured by Arizona Center for Advanced Medicine serving Arizona from Scottsdale. Phone 480-240-2600.
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High cholesterol? Do our bodies REALLY intend to hurt us?
The Federal Drug Administration (FDA) just came out with a warning about statin drugs causing memory loss and diabetes. Newspapers picked up this warning as though this were a recent development in the history of statin drug use.
In fact, we are finally recognizing officially what has been known by our patients for years – statins cause weakness, muscle pains, memory loss and contribute to the development of diabetes. Statins have been widely prescribed as a way of getting patients into the office for an annual check-up for many years.
In 1988, the American Medical Association’s Executive Vice-President, Dr. James Sammons, promised physicians their financial rewards stating, “The AMA’s campaign against cholesterol will bring both old and new patients to you for necessary testing, counseling and care.”
Might there be just a hair of grandstanding in that statement? Where is the image of the physician healer? Where is the high calling to the art of medicine?
And in the current punitive climate of the practice of medicine, if we fail to prescribe statin drugs to our patients with cholesterols over 200, we are admonished by our peers, and censured by our medical boards, for failing to follow “clinical guidelines” and “standard of practice”.
Somehow allopathic medicine has failed to recognize that statins operate by stopping the synthesis of cholesterol through inhibition of an enzyme called HMG CoA reductase. HMG CoA is a precursor of CoQ-10, one of the most important antioxidants in the body’s metabolism of toxins. If we have no CoQ-10, our mitochondria (energy factories) accumulate toxins which they cannot get rid of, resulting in toxicity to muscles, severe muscle pain and weakness, and even congestive heart failure – the heart has more mitochondria than any other tissue in the body.
Dr Martha Grout asks “So… take your Lipitor® or Crestor® every day? Encourage doctors to prescribe it for their pediatric patients over the age of 8? I don’t think so.”

See the FREE VIDEO, “Understanding Cholesterol”, click here >>
http://goo.gl/MWBFT
Check out the full articles below on cholesterol and heart disease, and make up your own mind. You do have a choice!
Dr Martha discusses ‘Cholesterol’, click here >>
http://goo.gl/FlQhw
Dr Martha discusses ‘Heart Disease’, click here >>
http://goo.gl/Li00K
Hear Dr Martha Grout’s interview on ‘Heart Dieaase and Cancer’ with George Noory of the Coast to Coast radio show . click here >>
http://goo.gl/4Mjlg
.
The Arizona Center for Advanced Medicine treats over 300+ conditions. Contact Arizona Center for Advanced Medicine for a FREE consultation at 480-240-2600, or email here >> info@Arizona AdvancedMedicine.com.

Find, Follow, LIKE and See us everywhere at ‘AdvancedMedAZ’.





















